Description
CN SPE Cartridge: Versatile Sorbent for Dual-Mode Extraction
The CN (cyanopropyl) solid-phase extraction (SPE) cartridge is a weakly hydrophobic silica-based sorbent that functions effectively in both normal-phase and reversed-phase chromatography. Its moderate polarity allows for the selective extraction of various compounds based on solvent conditions.
- Under reversed-phase conditions, it extracts non-polar, weakly polar, acidic, neutral, and basic compounds from aqueous solutions.
- Under normal-phase conditions, it retains polar compounds from non-polar organic solutions.
- The cyanopropyl functional group also acts as a complexing ligand, enabling the enrichment of specific metal ions in aqueous solutions.
This sorbent is particularly useful when strongly hydrophobic analytes irreversibly bind to C18 sorbents, making CN a more suitable alternative.
Key Features
- Compatible with biological matrices, ensuring effective extraction of analytes from complex samples
- Polarity can be adjusted by modifying the solvent ratio, providing flexible retention properties
- Enables metal ion enrichment in aqueous solutions, expanding its application beyond organic compound extraction
Applications
- Pharmaceutical and biomedical analysis
- Detection of drugs and their metabolites in body fluids, including sterols
- Food safety and agricultural testing
- Analysis of pesticide and veterinary drug residues in food and dairy products
- Environmental monitoring
- Identification of petroleum contaminants and pesticide residues in soil and water samples
The CN SPE cartridge provides balanced hydrophobic and polar interactions, making it a versatile and efficient choice for biomedical, environmental, and food safety applications.
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