Ion-Exchange PSA SPE Cartridge

R1,00

  • Functional Group: PSA phases are typically functionalized with primary (-NH₂) and secondary (-NHR) amine groups.
  • Retention Mechanism: Weak Anion Exchange (WAX), Lewis Base Interactions, Hydrophilic Interaction Liquid Chromatography (HILIC)
  • Particle size: 50-75μm
  • Average pore size: 100 Å
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Description

PSA SPE Cartridge: High-Capacity Sorbent for Weak Anion Exchange and Chelation

The PSA (primary-secondary amine) solid-phase extraction (SPE) cartridge is a polar adsorbent bonded to N-propylethylenediamine on a high-purity silica gel matrix. With two amino groups (primary and secondary amines), PSA exhibits stronger ion exchange capacity than NH2-based sorbents. The dual amino groups have high pKa values of 10.1 and 10.9, making PSA highly effective for weak anion exchange and chelation.

Compared to NH2 SPE cartridges, PSA offers:

  • Higher ion exchange capacity due to bidentate ligand properties, making it useful for metal ion extraction
  • Lower polarity, allowing it to retain polar compounds less strongly than NH2 sorbents
  • Greater carbon loading for improved extraction efficiency

Key Features

  • High-capacity design supports larger sample volumes while maintaining extraction efficiency
  • Greater ion exchange capacity than NH2 SPE cartridges
  • Effectively removes multiple interferences from food matrices
  • High-purity sorbent with a controllable surface area for stable and reproducible performance
  • No blank background interference, making it ideal for GC/MS and LC/MS analysis

Applications

  • Environmental and industrial analysis
    • Soil and water testing for organic contaminants and metal ions
  • Pharmaceutical and clinical research
    • Detection of sedatives in biological fluids such as plasma and urine
  • Food safety and agricultural analysis
    • Removal of fatty acids (oleic acid, palmitic acid, linoleic acid) that interfere with food analysis
    • Elimination of organic acids, pigments, metal ions, and carbohydrate interferences from food samples
  • Petroleum and chemical analysis
    • Separation and purification of specific compounds in complex hydrocarbon mixtures

The PSA SPE cartridge is a high-performance solution for weak anion exchange, chelation, and complex sample purification, making it valuable in food safety, environmental, pharmaceutical, and industrial applications.

 

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