Description
Mixed Mode Octyl (C8)/SAX SPE Cartridge: Dual-Retention Sorbent for Complex Sample Extraction
The Mixed Mode Octyl (C8)/SAX solid-phase extraction (SPE) cartridge is a hybrid sorbent that combines moderate hydrophobic retention with strong anion exchange properties. This dual-functionality is achieved through a proportionally bonded octyl (C8) group and a quaternary amine (SAX) group, allowing for selective retention of a wide range of compounds.
- The C8 functional group provides moderate hydrophobic interactions for non-polar and weakly polar compounds.
- The SAX (quaternary amine) group enables strong anion exchange for negatively charged analytes.
This mixed-mode cartridge is particularly useful when C8 or C18 sorbents cause excessive retention, or when SAX cartridges retain compounds too strongly, leading to elution difficulties.
Key Features
- Medium retention capacity, helping to improve elution efficiency for target compounds
- Ideal for processing complex biological matrices such as blood and urine
- Provides both hydrophobic and anion exchange interactions, enhancing selectivity for a broader range of compounds
Applications
- Pharmaceutical and clinical analysis
- Detection of drugs such as THC, making it useful in drug abuse screening
- Identification of drug metabolites in biological fluids, including blood and urine
- Forensic and toxicology testing
- Extraction and analysis of barbiturates and aryl benzoic acids from biological samples
The Mixed Mode Octyl (C8)/SAX SPE cartridge offers enhanced selectivity and versatility, making it a highly effective solution for pharmaceutical, forensic, and clinical sample extractions.
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