Description
Diol SPE Cartridge: Versatile Sorbent for Polar Compound Extraction
The Diol solid-phase extraction (SPE) cartridge is a weak anion exchanger designed for efficient polar compound retention. The diol-based sorbent consists of polar diol groups (-Si(CH2)3OCH2CH(OH)CH2OH) bonded to a silica gel matrix, offering medium polarity and hydrogen bonding interactions.
This cartridge can function as either a normal-phase or reversed-phase adsorbent, depending on the solvent system used. Unlike unmodified silica gel, the Diol sorbent has reduced acidity, making it ideal for analyte extraction without interference from alkaline impurities.
Key Features
- Alternative to silica gel SPE cartridges, eliminating retention of alkaline impurities
- Can function in both normal-phase and reversed-phase modes, offering flexible retention properties
- Provides hydrogen bonding interactions for enhanced selectivity of polar compounds
Applications
- Food and Agricultural Analysis
- Extraction and purification of pigments, phenols, and phospholipids in vegetable oils
- Pharmaceutical and Clinical Research
- Detection of drugs and metabolites in biological fluids such as urine
- Biochemical and Glycan Research
- Separation and purification of glycan mixtures for structural analysis
The Diol SPE cartridge is an effective alternative to silica gel-based sorbents, providing versatile retention properties for a wide range of polar analytes. Its dual functionality in normal-phase and reversed-phase chromatography makes it a valuable tool for complex sample preparation.
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